Vardenafil

This treatment is a medication that is used to treat erectile dysfunction, otherwise known as impotence. It belongs to a group of medications called PDE5 inhibitors, which all work to stop erectile dysfunction via similar mechanisms of action, which we will discuss later. Known by many different brand names, but most popularly known as Levitra, Staxyn, or Vivanza, this medication is what is known as an active ingredient in these brands, which is the part of the medication that is effective at treating erectile dysfunction.

It was first made available in 2003, at similar times to other erectile dysfunction medications such as Tadalafil and Sildenafil Citrate. It was manufactured and marketed jointly by the pharmaceutical giants Bayer Pharmaceuticals, GlaxoSmithKline, and Schering-Plough under the trade name Levitra. From 2005 onwards, it was also manufactured as Vivanza in many markets, where it can often be found under both brand names.

On 31 October 2018, the patent for this medication expired. This then allowed different pharmaceutical companies to manufacture generic versions of the medications. Because these pharmaceutical companies did not have to pay to spend money developing the medication, running trials on the medication to check its safety, and advertising it to different markets, they manage to save a lot of money. This money can then be passed on directly to consumers, allowing them to buy Vardenafil at much cheaper prices, while the generic version remains just as effective.

What is vardenafil used for other than that and are there side-effect to the medicine? Read on to find out.

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What is Vardenafil Used For?

Vardenafil tablets are used to treat erectile dysfunction, otherwise known as impotence. This condition is something that affects men all over the world, to wildly different degrees depending on location, and the study. One scientific study conducted in 2019, studied randomly selected 45-year-old men. In total, 10,135 Caucasian, heterosexual, sexually active men were included in the study to find out how prevalent erectile dysfunction was amongst this particular group.

It found that amongst the men who took part in the study, approximately 25.2% of them had some level of erectile dysfunction. This was broken down into the following levels of erectile dysfunction - 8.7% of them had mild, 4.2% of them had mild to moderate, 9.2% of them had moderate and 3.1% of them had severe erectile dysfunction. It also found that among those who suffered from this condition, 48.8% of them had moderate to severe symptoms.

Additionally, that the prevalence of suffering from erectile dysfunction increased in those with at least 5-8 risk factors (such as obesity, smoking, depression, diabetes, physical inactivity, etc.), to 68.8% of study participants. Out of these, the strongest link to erectile dysfunction was those who were suffering from depression. This study shows just how common a seemingly 'embarrassing' condition such as erectile dysfunction truly is, hence why so many people try to buy Vardenafil online.

It is difficult to say exactly what is defined as erectile dysfunction as a medical condition, and how someone would differentiate what constitutes mild symptoms to what constitutes moderate symptoms. That is why the above study, and many other studies such as it, use the Erectile Function domain of the International Index of Erectile Function. This is a self-reporting questionnaire that asks how your sex life has been affected over the previous four weeks by erectile issues.

There are 15 questions which you can rate your answer between 1 to 5, with 1 being more indicative of issues with erectile and sexual function, and 5 being not indicative at all. For someone who scores under half of the maximum score for the questions relating to erectile function, a trial of a prescription medication such as this one is considered.

As previously mentioned, there are risk factors which increases the chance of suffering from erectile dysfunction. Some of these risk factors are:

  • Psychological disorders, such as depression, anxiety, or schizophrenia
  • Diabetes
  • Cardiovascular disease
  • High Blood Pressure
  • Curvature of the penis caused by scar tissue—Peyronie's disease
  • Endocrine disorders such as hypogonadism, hypothyroidism, hyperprolactinemia, or Cushing syndrome
  • Neurological disorders such as multiple sclerosis, peripheral neuropathy, or stroke

That is not to say that people without these risk factors cannot also suffer from erectile dysfunction, it just makes it much more likely. For the physical risk factors, this is usually due to a blocking or hardening of the blood vessels. When this occurs, not at much blood is able to make it through the blood vessels to the penis, meaning that it is less able to become engorged and hardened due to insufficient blood reaching it.

How Does Vardenafil Work?

Vardenafil tablets work in the same as many other PDE-5 inhibitors. PDE-5 stands for phosphodiesterase type 5, which is an enzyme that is present in the smooth muscle of the corpus cavernosum. It affects blood flow and how cells signal within the body. Once the medication enters the bloodstream, the PDE-5 enzyme is inhibited, and an enzyme called cGMP (cyclic guanosine monophosphate) is prevented from breaking down. This increases in the effectiveness of cGMP, which relaxes the smooth muscle.

Once this smooth muscle is relaxed, the blood vessels widen, which allowed more blood to flow throughout the body, by enhancing the nitric oxide in the body. Unfortunately, the treatment and other PDE-5 inhibitors do not increase libido. Sexual arousal is needed regardless of taking a tablet for this medication to work.

How Long Does Vardenafil Last?

So, how does vardenafil work against your erectile dysfunction? After consumption, the treatment quickly enters the bloodstream via the gastrointestinal tract. The effects of this medication take between 25 to 60 minutes to kick in after consumption. Following consumption, this medication's effects last for around 5 hours. The half-life of this medication, which is how long it takes for half of the medication to leave the body, is between 4 and 5 hours. There are different factors however that can affect how long vardenafil lasts. These are:

  • Dosage - the higher the dose, the more likely it is that the effects of the medication will last for longer. It is not recommended to take more than is strictly necessary however, as higher doses of any medication can result in more side effects. You should never take more than the recommended maximum daily dosage per day.
  • Excess smoking, drinking or substance abuse - all these factors can be direct contributors towards affecting the severity of someone's erectile dysfunction. If someone partakes in these to excess, it can result in the medicine's effects being less potent than in someone who did not have these risk factors considered.
  • Other medications - some medications make affect how long the effect lasts when taken in conjunction with it. One in particular is erythromycin, a common antibiotic.

Vardenafil Dosage Instructions

This medication should be taken whole, with a glass of water, prior to any sexual activity. You should not take the treatment alongside a large or fatty meal, as this can affect how long it takes for the medication to work, how effective it is, and how long it works for.

The recommended starting dosage is 10mg. A vardenafil dosage of 20 mg is also available. You should take as much of this medication as you need in order to achieve an erection strong enough for sexual activity, but you should not exceed the maximum daily dose of 20mg per day. If you feel that 10mg is still too strong, or it is not necessary for you to take this much, you can split a dose into 5mg, which reduces the very low risk of side effects even further.

Vardenafil Side Effects

As previously mentioned, the risk of side effects is very low, but can still occur, especially when taking the higher doses. The best way to cope with side effects when taking medications is to educate yourself about which you can expect, and whether what you are currently experiencing is in line with Vardenafil side effects. Some of the more common side effects are:

  • headache
  • gastrointestinal issues
  • heartburn
  • acid reflux
  • flushing
  • stuffy or runny nose

There can also be rarer, more severe symptoms. If any of the following symptoms occur, you must call your doctor:

  • priapism, which is an erection lasting for longer than four hours
  • changes in vision
  • sudden decrease in hearing
  • dizziness
  • fainting
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Please note that the above list is not a complete list of side effects.

One of the most important side effect symptoms to watch out for is related to allergic reactions. When someone experiences an allergic reaction from taking a medication, it is very important that they receive medical assistance immediately. Some common allergic reaction symptoms are rashes, itching/swelling, severe dizziness, and trouble breathing. Please observe your advised vardenafil dosage.

How Safe Is Vardenafil?

The treatment is a very safe medication and vardenafil benefits are immeasurable, however, there are some people who should seek medical advice, or refrain entirely from taking this medication. Those who should at least consult their doctor first are:

  • People who are taking nitrates. If you are taking any nitrate medication, or medication that increases the effectiveness of nitrates, you should not take this medication. It can dramatically cause a dangerous drop in blood pressure. Likewise, taking street drugs such as amyl nitrate and butyl nitrate can cause the same effects.
  • Women. This medication is only designed to be taken by men and has not been tested or proven to be effective when taken by women, especially if they are pregnant and/or breastfeeding.
  • If you tend to eat a lot of grapefruit, or drink a lot of grapefruit juice, you should be careful when taking this medication. It can interact with this medication and potentially cause unwanted side effects.

Vardenafil vs Viagra

Does vardenafil work against erectile dysfunction in comparison to Viagra? We get asked that a lot. If you are unsure of the difference between these two medications, then we will try to explain here. Viagra is the more famous of the two medications, due to the large marketing budget that Pfizer spent when initially bringing this medication out. Despite this, they are both PDE-5 inhibitors, which work to treat erectile dysfunction. In relation to differences, the medicine works for longer than Viagra, and has a longer half-life.

It is also stronger than Viagra, so where 50mg of Viagra is the standard dose for impotence, with this treatment, 10mg is the standard dose. Furthermore, the risk of side effects for both medications are low, but the incidence seems to be slightly lower when taking the medicine, rather than Viagra. This might be the reason why more people than ever are starting to buy vardenafil online.

Before You Buy Vardenafil Online

Before you buy this medicine, you should see if there are other methods to treat your erectile dysfunction first and compare their advantages to vardenafil benefits. Online research on subjects such as 'what is vardenafil?' can also help you collect more information about the treatment. Medication should never usually be the first way of treating something, due to the cost and the potential risk of side effects. Some alternative methods of treating erectile dysfunction are:

  • Penis pumps - a penis pump works by drawing blood into the penis via suction. Once the blood enters the penis, it helps it to become hard. Although this is a way of achieving an erection without taking medication, the effect of this device only lasts for around 30 minutes. Additionally, if you are embarrassed of having erectile dysfunction, and do not want the person that you are having sexual activity to know about it, then it is not a very subtle method of treating it.
  • Exercise - leading a healthier lifestyle in general is a good indicator for a reduced risk of having erectile dysfunction. Regular exercise in particular has been shown to help with increased blood flow.
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Buy Vardenafil Online

So, if you are looking to buy Vardenafil online from a reliable source, then look no further. Here at onlinekamagra.com, we not only allow you to buy Vardenafil online, but also a whole range of other erectile dysfunction medications. If you are embarrassed to go to your doctor to obtain a prescription for the treatment, you can obtain this and many other medications from us here. We deliver and send all our products in very discreet packaging, so nobody will know what you are ordering.

If you are interested in our range of vardenafil products, then please do not hesitate to contact us online via our Contact Us page, where we will be happy to help with any query that you have.

Dr. Reginald Smythe (MChE)
Reviewed by:

Dr. Reginald Smythe (MChE)

Dr Smythe has been in the medical industry his whole adult life. As a child, he was a very quiet boy who enjoyed reading and climbing trees. As a young adult, he developed a passion for chemistry and his curiosity even had him creating his own fireworks.

Checked: 17th July 2024
Review Due: August 2025

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